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Weight Loss and Control Health Risks of Overweight


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Health Risks of Overweight

Weighing too much may increase your risk for developing many health problems. If you are overweight or obese on a body mass index (BMI) chart (see page 2), you may be at risk for:

    Type 2 diabetes

    Heart disease and stroke

    Cancer

    Sleep apnea

    Osteoarthritis

    Gallbladder disease

    Fatty liver disease.

You can lower your health risks by losing as little as 10 to 20 pounds.

Type 2 diabetes

What is it?

Type 2 diabetes used to be called adult-onset diabetes or noninsulin-dependent diabetes. It is the most common type of diabetes in the U.S. Type 2 diabetes is a disease in which blood sugar levels are above normal. High blood sugar is a major cause of early death, heart disease, kidney disease, stroke, and blindness.

How is it linked to overweight?

More than 80 percent of people with type 2 diabetes are overweight. It is not known exactly why people who are overweight are more likely to suffer from this disease. It may be that being overweight causes cells to change, making them less effective at using sugar from the blood. This then puts stress on the cells that produce insulin (a hormone that carries sugar from the blood to cells) and makes them gradually fail.

What can weight loss do?

You can lower your risk for developing type 2 diabetes by losing weight and increasing the amount of physical activity you do. If you have type 2 diabetes, losing weight and becoming more physically active can help you control your blood sugar levels. Losing weight and exercising more may also allow you to reduce the amount of diabetes medication you take.

Heart disease and stroke

What is it?

Heart disease means that the heart and circulation (blood flow) are not functioning normally. If you have heart disease, you may suffer from a heart attack, congestive heart failure, sudden cardiac death, angina (chest pain), or abnormal heart rhythm. During a stroke, blood and oxygen do not flow normally to the brain, possibly causing paralysis or death. Heart disease is the leading cause of death in the U.S., and stroke is the third leading cause.

How is it linked to overweight?

People who are overweight are more likely to suffer from high blood pressure, high levels of triglycerides (blood fats) and LDL cholesterol (a fat-like substance often called the “bad cholesterol”), and low levels of HDL cholesterol (the “good cholesterol”). These are all risk factors for heart disease and stroke. In addition, people with more body fat have higher blood levels of substances that cause inflammation. Inflammation in blood vessels and throughout the body may raise heart disease risk.

What can weight loss do?

Losing 5 to 15 percent of your weight can lower your chances for developing heart disease or having a stroke. If you weigh 200 pounds, this means losing as little as 10 pounds. Weight loss may improve your blood pressure, triglyceride, and cholesterol levels; improve how your heart works and your blood flows; and decrease inflammation throughout your body.

Body Mass Index Table

To use the table, find the appropriate height in the left-hand column labeled Height. Move across to a given weight. The number at the of the column is the BMI at that height and weight. Pounds have been rounded off.

 

BMI

19

20

21

22

23

24

25

26

27

28

29

30

31

32

33

34

35

36

37

38

39

40

Weight
(Pounds)

Height
(Inches)

                                           

58

91

96

100

105

110

115

119

124

129

134

138

143

148

153

158

162

167

172

177

181

186

191

59

94

99

104

109

114

119

124

128

133

138

143

148

153

158

163

168

173

178

183

188

193

198

60

97

102

107

112

118

123

128

133

138

143

148

153

158

163

168

174

179

184

189

194

199

204

61

100

106

111

116

122

127

132

137

143

148

153

158

164

169

174

180

185

190

195

201

206

211

62

104

109

115

120

126

131

136

142

147

153

158

164

169

175

180

186

191

196

202

207

213

218

63

107

113

118

124

130

135

141

146

152

158

163

169

175

180

186

191

197

203

208

214

220

225

64

110

116

122

128

134

140

145

151

157

163

169

174

180

186

192

197

204

209

215

221

227

232

65

114

120

126

132

138

144

150

156

162

168

174

180

186

192

198

204

210

216

222

228

234

240

66

118

124

130

136

142

148

155

161

167

173

179

186

192

198

204

210

216

223

229

235

241

247

67

121

127

134

140

146

153

159

166

172

178

185

191

198

204

211

217

223

230

236

242

249

255

68

125

131

138

144

151

158

164

171

177

184

190

197

204

210

216

223

230

236

243

249

256

262

69

128

135

142

149

155

162

169

176

182

189

196

203

210

216

223

230

236

243

250

257

263

270

70

132

139

146

153

160

167

174

181

188

195

202

209

216

222

229

236

243

250

257

264

271

278

71

136

143

150

157

165

172

179

186

193

200

208

215

222

229

236

243

250

257

265

272

279

286

72

140

147

154

162

169

177

184

191

199

206

213

221

228

235

242

250

258

265

272

279

287

294

73

144

151

159

166

174

182

189

197

204

212

219

227

235

242

250

257

265

272

280

288

295

302

74

148

155

163

171

179

186

194

202

210

218

225

233

241

249

256

264

272

280

287

295

303

311

75

152

160

168

176

184

192

200

208

216

224

232

240

248

256

264

272

279

287

295

303

311

319

76

156

164

172

180

189

197

205

213

221

230

238

246

254

263

271

279

287

295

304

312

320

328

Cancer

What is it?

Cancer occurs when cells in one part of the body, such as the colon, grow abnormally or out of control and possibly spread to other parts of the body, such as the liver. Cancer is the second leading cause of death in the U.S.

How is it linked to overweight?

Being overweight may increase the risk of developing several types of cancer, including cancers of the colon, esophagus, and kidney. Overweight is also linked with uterine and postmenopausal breast cancer in women. Gaining weight during adult life increases the risk for several of these cancers. Being overweight also may increase the risk of dying from some cancers. It is not known exactly how being overweight increases cancer risk. It may be that fat cells make hormones that affect cell growth and lead to cancer. Also, eating or physical activity habits that may lead to being overweight may also contribute to cancer risk.

What can weight loss do?

Avoiding weight gain may prevent a rise in cancer risk. Weight loss, and healthy eating and physical activity habits, may lower cancer risk.

Sleep apnea

What is it?

Sleep apnea is a condition in which a person stops breathing for short periods during the night. A person who has sleep apnea may suffer from daytime sleepiness, difficulty concentrating, and even heart failure.

How is it linked to overweight?

The risk for sleep apnea is higher for people who are overweight. A person who is overweight may have more fat stored around his or her neck. This may make the airway smaller. A smaller airway can make breathing difficult, loud (snoring), or stop altogether. In addition, fat stored in the neck and throughout the body can produce substances that cause inflammation. Inflammation in the neck may be a risk factor for sleep apnea.

What can weight loss do?

Weight loss usually improves sleep apnea. Weight loss may help to decrease neck size and lessen inflammation.

Osteoarthritis

What is it?

Osteoarthritis is a common joint disorder. With osteoarthritis, the joint bone and cartilage (tissue that protects joints) wear away. Osteoarthritis most often affects the joints of the knees, hips, and lower back.

How is it linked to overweight?

Extra weight may place extra pressure on joints and cartilage, causing them to wear away. In addition, people with more body fat may have higher blood levels of substances that cause inflammation. Inflammation at the joints may raise the risk for osteoarthritis.

What can weight loss do?

Weight loss can decrease stress on your knees, hips, and lower back, and lessen inflammation in your body. If you have osteoarthritis, losing weight may help improve your symptoms.

Gallbladder disease

What is it?

Gallstones are clusters of solid material that form in the gallbladder. They are made mostly of cholesterol and can sometimes cause abdominal or back pain.

How is it linked to overweight?

People who are overweight have a higher risk for developing gallbladder disease and gallstones. They may produce more cholesterol, a risk factor for gallstones. Also, people who are overweight may have an enlarged gallbladder, which may not work properly.

What can weight loss do?

Weight loss — especially fast weight loss (more than 3 pounds per week) or loss of a large amount of weight — can actually increase your chance of developing gallstones. Modest, slow weight loss of about 1/2 to 2 pounds a week is less likely to cause gallstones.

Fatty liver disease

What is it?

Fatty liver disease occurs when fat builds up in the liver cells and causes injury and inflammation in the liver. It can sometimes lead to severe liver damage, cirrhosis (build-up of scar tissue that blocks proper blood flow in the liver), or even liver failure. Fatty liver disease is like alcoholic liver damage, but it is not caused by alcohol and can occur in people who drink little or no alcohol.

How is it linked to overweight?

People who have diabetes or “pre-diabetes” (when blood sugar levels are higher than normal but not yet in the diabetic range) are more likely to have fatty liver disease than people without these conditions. And people who are overweight are more likely to have diabetes (see Type 2 diabetes above). It is not known why some people who are overweight or diabetic get fatty liver and others do not.

What can weight loss do?

Losing weight can help you control your blood sugar levels. It can also reduce the build-up of fat in your liver and prevent further injury. People with fatty liver disease should avoid drinking alcohol.

How can I lower my health risks?

If you are overweight, losing as little as 5 percent of your body weight may lower your risk for several diseases, including heart disease and diabetes. If you weigh 200 pounds, this means losing 10 pounds. Slow and steady weight loss of 1/2 to 2 pounds per week, and not more than 3 pounds per week, is the safest way to lose weight.

To lose weight and keep it off over time, try to make long-term changes in your eating and physical activity habits. Choose healthy foods, such as vegetables, fruits, whole grains, and low-fat meat and dairy products, more often and eat just enough food to satisfy you. Try to do at least 30 minutes of moderate-intensity physical activity—like walking—on most days of the week, preferably every day. To lose weight, or to maintain weight loss, you may need to do more than 30 minutes of moderate physical activity daily.

Additional resources

National Cancer Institute
NCI Public Inquiries Office
Suite 3036A
6116 Executive Boulevard, MSC8322
Bethesda, MD 20892-8322
Phone: 1-800-4-CANCER (1-800-422-6237)
TTY: 1-800-332-8615

www.nci.nih.gov

National Diabetes Information Clearinghouse
1 Information Way
Bethesda, MD 20892-3560
Phone: 1-800-860-8747 or (301) 654-3327

http://diabetes.niddk.nih.gov

National Digestive Diseases Information Clearinghouse
2 Information Way
Bethesda, MD 20892-3570
Phone: 1-800-891-5389 or (301) 654-3810

http://digestive.niddk.nih.gov

National Heart, Lung, and Blood Institute
NHLBI Health Information Center
P.O. Box 30105
Bethesda, MD 20824-0105
Phone: (301) 592-8573
TTY: (240) 629-3255

www.nhlbi.nih.gov

National Institute of Arthritis and Musculoskeletal and Skin Diseases
Information Clearinghouse
1 AMS Circle
Bethesda, Maryland 20892-3675
Phone: 1-877-22-NIAMS (1-877-226-4267) or (301) 495-4484
TTY: (301) 565-2966

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Last updated: January 2004.

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