HERBS: Ginseng (American)

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Ginseng (American)

Panax quinquefolius

Xi yang shen, Tienchi ginseng, western ginseng, five-fingers

To improve athletic performance: No scientific evidence supports this use.
To prevent and treat cancer: No scientific evidence supports this use.
To treat diabetes: A handful of studies show a blood glucose-lowering effect of American ginseng in humans, but there is not enough evidence to support replacing diabetes medications with American ginseng.
To stimulate the immune system: Some studies show an immunostimulant effect in animals. There is no proof from clinical trials that this effect occurs in humans.
For increased strength and stamina: Although ginseng is often promoted for this use, there is no proof from clinical trials that this effect occurs in humans.

No significant reactions reported

Monoamine oxidase inhibitors (MAOIs): American ginseng may cause manic-like symptoms when combined with MAOIs.
Insulin and sulfonylureas: American ginseng may increase the hypoglycemic effect of insulin and sulfonylureas.
Anticoagulants: Theoretically, American ginseng may antagonize the effects of anticoagulants.

1. Huang KC. The Pharmacology of Chinese Herbs, 2nd ed. New York: CRC Press; 1999.

7. Brinker F. Herb Contraindications and Drug Interactions, 3rd ed. Sandy (OR): Eclectic Medical Publications; 2001.